Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329916 | 0.86 | KDM4E (0.50) | KDM4EGPR3CA1CA2CA9 | |
| SCHEMBL27636764 | 0.86 | CA2 (0.56) | KDM4EGPR3CA1CA2CA9 | |
| SCHEMBL329917 | 0.84 | KDM4E (0.49) | KDM4EGPR3CA1CA2CA9 | |
| SCHEMBL30857515 | 0.78 | KDM4E (0.61) | KDM4EGPR3CYP1A2ALDH1A1LMNA | |
| SCHEMBL28289329 | 0.77 | KDM4E (0.55) | KDM4EGPR3CA9CYP1A2ALDH1A1 | |
| Benzene SCHEMBL12471481 | 0.76 | ALDH1A1 (0.51) | KDM4EGPR3CA1CA2CA9 | |
| Phenanthridine SCHEMBL11872956 | 0.76 | GPR3 (0.77) | KDM4EGPR3CA1CA2CA9 | |
| SCHEMBL329543 | 0.75 | KDM4E (0.57) | KDM4EGPR3HTTCYP1A2ALDH1A1 | |
| SCHEMBL840361 | 0.75 | KDM4E (0.57) | KDM4EGPR3HTTCYP1A2ALDH1A1 | |
| SCHEMBL6590915 | 0.73 | KDM4E (0.59) | KDM4EGPR3CA9CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030631-A | Hypotensive, bronchodilator agents | SCHERING CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| US-3959100-A | OPACIFIER | SCM CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |