Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501818 | 0.79 | FFAR1 (0.59) | FFAR1GAAALDH1A1L3MBTL1USP5 | |
| SCHEMBL9780297 | 0.74 | ALDH1A1 (0.43) | FFAR1CYSLTR2CYSLTR1GAAALDH1A1 | |
| SCHEMBL9780294 | 0.74 | ALDH1A1 (0.43) | FFAR1CYSLTR2CYSLTR1GAAALDH1A1 | |
| SCHEMBL10766420 | 0.74 | FFAR1 (0.38) | FFAR1GABBR2GABBR1CYP2C9CYP1A2 | |
| SCHEMBL9863050 | 0.73 | CYSLTR2 (0.36) | FFAR1CYSLTR2CYSLTR1GAAALDH1A1 | |
| SCHEMBL9734675 | 0.73 | CYSLTR2 (0.41) | FFAR1CYSLTR2CYSLTR1GAAALDH1A1 | |
| SCHEMBL25575108 | 0.73 | L3MBTL1 (0.49) | FFAR1GAAALDH1A1L3MBTL1GABBR2 | |
| SCHEMBL9732958 | 0.72 | POLB (0.51) | FFAR1CYSLTR2CYSLTR1GAAALDH1A1 | |
| SCHEMBL11823552 | 0.72 | MME (0.47) | FFAR1 | |
| SCHEMBL20366132 | 0.72 | L3MBTL1 (0.61) | GAAALDH1A1L3MBTL1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990526-A | Skin disorders, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1991-02-05 | — | — | US | disclosed |
| EP-0219308-A2 | 2-Substituted quinolines | MERCK FROSST CANADA INC. (CA) | 1987-04-22 | — | — | EP | disclosed |
| EP-0206741-A2 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |