Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882576 | 0.83 | IRAK4 (0.44) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL2335765 | 0.80 | IRAK4 (0.43) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8980659 | 0.78 | NNMT (0.38) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL728753 | 0.78 | CYP1A2 (0.48) | ALDH1A1MAPTKDM4EHPGDTSHR | |
| SCHEMBL27676583 | 0.76 | IRAK4 (0.36) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL2977145 | 0.74 | IRAK4 (0.50) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8011592 | 0.74 | IRAK4 (0.38) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL28887386 | 0.74 | SIRT3 (0.40) | IRAK4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8981463 | 0.73 | IRAK4 (0.53) | IRAK4ALDH1A1MAPTTDP1PARP10 | |
| SCHEMBL28882111 | 0.73 | IRAK4 (0.37) | IRAK4ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |