Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780893 | 0.83 | SCN9A (0.33) | SCN9ALCK | |
| SCHEMBL4979889 | 0.83 | MAPK8 (0.36) | SCN9APARP1MEN1KMT2ACYP3A4 | |
| SCHEMBL29976932 | 0.81 | SCN9A (0.38) | SCN9ARARBRARGMEN1KMT2A | |
| SCHEMBL3897421 | 0.80 | ACE2 (0.47) | SCN9ARARBRARGTSHRHSD17B10 | |
| SCHEMBL28388301 | 0.80 | HRH4 (0.46) | LCKPARP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28381769 | 0.79 | HRH4 (0.39) | PARP1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL9781007 | 0.79 | PARP10 (0.37) | LCKPARP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10918140 | 0.79 | PKM (0.43) | LCKPARP1TSHRHTR1AHTR1D | |
| SCHEMBL29773094 | 0.78 | SCN9A (0.44) | SCN9APARP1TSHRMEN1KMT2A | |
| SCHEMBL28093978 | 0.78 | SCN9A (0.44) | SCN9APARP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |