Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782208 | 0.84 | ADRB3 (0.47) | ADRB3SMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL9782191 | 0.84 | ADRB3 (0.49) | ADRB3SMN1; SMN2KDM4EGAATDP1 | |
| Oxalic Acid SCHEMBL9787715 | 0.83 | ADRB3 (0.49) | ADRB3SMN1; SMN2KDM4EGAATDP1 | |
| SCHEMBL9782106 | 0.82 | ADRB1 (0.49) | ADRB3ADRB2ADRB1 | |
| SCHEMBL10430916 | 0.81 | ADRB3 (0.47) | ADRB3SMN1; SMN2ADRB2ADRB1DRD3 | |
| SCHEMBL9782146 | 0.81 | ADRB1 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9782091 | 0.80 | THRA (0.40) | ADRB3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9782109 | 0.79 | THRA (0.38) | ADRB3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9782267 | 0.79 | ADRB2 (0.51) | ADRB3ADRB2ADRB1ALDH1A1 | |
| SCHEMBL9813897 | 0.77 | ADRB3 (0.64) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988714-A | Drugs for treatment of obesity and diabetics, increases protein breakdown, for fattening animals | HOFFMANN-LA ROCHE INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4800206-A | ANTIDIABETIC AGENTS; HYPOGLYCEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1989-01-24 | — | — | US | disclosed |