Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14809551 | 0.86 | MAPT (0.43) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL9672478 | 0.84 | MAPT (0.42) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL9671321 | 0.84 | MAPT (0.42) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL4065281 | 0.84 | MAPT (0.42) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL158378 | 0.84 | MAPT (0.42) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL27405623 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL907623 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL5067985 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL74445 | 0.79 | L3MBTL1 (0.50) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL24425956 | 0.77 | PDE4A (0.51) | MAPTALDH1A1KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |