SCHEMBL74445

SCHEMBL74445

CCOC(=O)C1CCCNC1=O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
HSD17B10 Q99714 2/20 0.47
TLR4 O00206 1/20 0.46
POLB P06746 2/20 0.44
ALDH1A1 P00352 4/20 0.43
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.41
LMNA P02545 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940890 0.94 L3MBTL1 (0.45) L3MBTL1HSD17B10TLR4POLBALDH1A1
SCHEMBL3193620 0.90 L3MBTL1 (0.42) L3MBTL1HSD17B10TLR4POLBALDH1A1
SCHEMBL8826699 0.90 FKBP5 (0.43) L3MBTL1HSD17B10TLR4POLBALDH1A1
SCHEMBL907623 0.90 MAPT (0.45) HSD17B10TLR4POLBALDH1A1MAPT
SCHEMBL27405623 0.90 MAPT (0.45) HSD17B10TLR4POLBALDH1A1MAPT
SCHEMBL20553752 0.87 HSD17B10 (0.57) L3MBTL1HSD17B10POLBALDH1A1MEN1
SCHEMBL24878938 0.83 L3MBTL1 (0.42) L3MBTL1HSD17B10TLR4POLBALDH1A1
SCHEMBL2789189 0.81 L3MBTL1 (0.54) L3MBTL1HSD17B10POLBALDH1A1MEN1
SCHEMBL14094291 0.80 HSD17B10 (0.46) L3MBTL1HSD17B10POLBALDH1A1MEN1
SCHEMBL14094109 0.79 CCR2 (0.45) L3MBTL1HSD17B10POLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108484484-B Preparation method of 2-oxo-3-ethyl piperidinecarboxylate 上海泾维化工科技有限公司 2021-01-05 CN claimed
US-20180326407-A1 Olefin polymerization catalyst components and process for the production of olefin polymers therewith FORMOSA PLASTICS CORPORATION, USA 2018-11-15 US claimed
US-10124324-B1 Olefin polymerization catalyst components and process for the production of olefin polymers therewith FORMOSA PLASTICS CORPORATION, USA (US) 2018-11-13 US claimed
EP-2262845-A1 MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS University of Southern Mississippi (US) 2010-12-22 EP claimed
US-20100163070-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE L'OREAL S.A. (FR) 2010-07-01 US claimed
US-20090208553-A1 Monomers and Polymers with Covalently - Attached Active Ingredients UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2009-08-20 US claimed
WO-2009102795-A1 MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2009-08-20 WO claimed
EP-0552360-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP claimed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO claimed
US-5167941-A Sulfur dioxide; cationic polyelectrolyte stabilizers THE DOW CHEMICAL COMPANY (US) 1992-12-01 US claimed
US-12637680-B2 Recombinant host cells for the production of malonate LYGOS, INC. (US) 2026-05-26 US disclosed
EP-4741397-A1 FUSED TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen Zhongge Biological Technology Co., Ltd. (CN) 2026-05-13 EP disclosed
EP-4629980-A1 ANTIMICROBIAL COMPOUNDS SRI International (US) 2025-10-15 EP disclosed
US-12421232-B2 Kinase inhibitor compounds and compositions and methods of use ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2025-09-23 US disclosed
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof RECREO PHARMACEUTICALS LLC (US) 2025-07-29 US disclosed
WO-1993024519-A1 LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY ZENECA LIMITED (GB) 1993-12-09 WO disclosed
EP-0552360-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-07-28 EP disclosed
WO-1993003825-A1 A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO disclosed
US-5167941-A Sulfur dioxide; cationic polyelectrolyte stabilizers THE DOW CHEMICAL COMPANY (US) 1992-12-01 US disclosed
US-3987183-A TRANSFERASE INHIBITOR, TREATMENT OF MENTAL ABERRATIONS AS SCHIZOPHRENIA MERCK & CO., INC. (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof CBR3, CBR1, CYP2B6 L3MBTL1 1925/4885HSD17B10 928/4885TLR4 3751/4885
US-12421232-B2 Kinase inhibitor compounds and compositions and methods of use CSNK1A1, DYRK1A, CSNK1G3 L3MBTL1 3307/4885HSD17B10 2393/4885TLR4 4741/4885
US-12637680-B2 Recombinant host cells for the production of malonate DCXR, ETV1, LYPLA2 L3MBTL1 236/4885HSD17B10 155/4885TLR4 936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.