SCHEMBL9782808

SCHEMBL9782808

Cc1cn([C@H]2C[C@H](OP(O)N(C)N(C(C)C)C(C)C)[C@@H](CNC(=O)OCC3c4ccccc4-c4ccccc43)O2)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10489355 0.93 RNASE1 (0.47) RNASE1
SCHEMBL9693232 0.89 DUT (0.38)
SCHEMBL9782837 0.89 RNASE1 (0.41) RNASE1
SCHEMBL9782858 0.85 RNASE1 (0.42) RNASE1
SCHEMBL9693305 0.85 RNASE1 (0.42) RNASE1
SCHEMBL8725738 0.82
SCHEMBL9693301 0.80 DOT1L (0.38)
SCHEMBL9693591 0.78 DUT (0.36)
SCHEMBL14718793 0.77 RNASE1 (0.52) RNASE1
SCHEMBL9342953 0.77 RNASE1 (0.44) RNASE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4849513-A Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-07-18 US claimed
US-5015733-A Phosphoramidites and oligonucleotides derived therefrom CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1991-05-14 US disclosed
US-4849513-A Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-07-18 US disclosed