Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693587 | 0.86 | DOT1L (0.38) | DOT1LADORA1ADORA3ADORA2A | |
| SCHEMBL9663874 | 0.82 | ADORA3 (0.44) | DOT1LADORA1ADORA3ADORA2A | |
| SCHEMBL9693232 | 0.81 | DUT (0.38) | DOT1L | |
| SCHEMBL9782808 | 0.80 | RNASE1 (0.45) | — | |
| SCHEMBL10489350 | 0.77 | PRKAG1 (0.33) | ADORA1ADORA2A | |
| SCHEMBL10489355 | 0.73 | RNASE1 (0.47) | — | |
| SCHEMBL9693591 | 0.72 | DUT (0.36) | DOT1L | |
| SCHEMBL16245122 | 0.72 | ADORA3 (0.38) | ADORA1ADORA3ADORA2A | |
| SCHEMBL19840344 | 0.71 | ADORA3 (0.37) | DOT1LADORA1ADORA3ADORA2A | |
| SCHEMBL9782837 | 0.71 | RNASE1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015733-A | Phosphoramidites and oligonucleotides derived therefrom | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |