Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 6/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020554 | 0.78 | MAPK1 (0.50) | PAOXKDM4EMAPK1HIF1AALDH1A1 | |
| SCHEMBL18227026 | 0.77 | ALDH1A1 (0.52) | ZDHHC7ALDH1A1 | |
| SCHEMBL23159100 | 0.75 | PAOX (0.47) | ZDHHC7TLR2PAOXKDM4EMAPK1 | |
| SCHEMBL28429637 | 0.74 | DNM1 (0.48) | TLR2ALDH1A1CNR1 | |
| SCHEMBL8663554 | 0.74 | DNM1 (0.54) | TLR2ALDH1A1CNR1 | |
| SCHEMBL20365078 | 0.74 | KDM4E (0.52) | ZDHHC7PAOXKDM4EMAPK1HIF1A | |
| SCHEMBL9151394 | 0.74 | ALDH1A1 (0.44) | TLR2ALDH1A1CNR1EPHX1 | |
| SCHEMBL25175787 | 0.73 | FFAR4 (0.51) | TLR2ALDH1A1 | |
| SCHEMBL24024 | 0.73 | MEN1 (0.42) | ALDH1A1CNR1 | |
| SCHEMBL16872540 | 0.73 | GPR84 (0.36) | ZDHHC7TLR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997984-A | Process for preparation of N-(α-alkoxyethyl)-carboxylic acid amide | SHAWA DENKO K.K. (JP) | 1991-03-05 | — | — | US | disclosed |