Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.51 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663731 | 0.82 | PCSK9 (0.63) | LPLLIPGPCSK9SIGMAR1 | |
| SCHEMBL5710442 | 0.77 | PCSK9 (0.55) | LPLLIPGPCSK9DRD2DRD3 | |
| Tetrabuthylammonium SCHEMBL5468630 | 0.75 | LPL (0.45) | LPLLIPGPCSK9SIGMAR1KCNH2 | |
| SCHEMBL5802656 | 0.75 | PCSK9 (0.53) | LPLLIPGPCSK9DRD2DRD3 | |
| SCHEMBL1040896 | 0.75 | MAOA (0.50) | MAOAMAOBSIGMAR1 | |
| SCHEMBL23367835 | 0.75 | PCSK9 (0.53) | LPLLIPGPCSK9DRD2DRD3 | |
| SCHEMBL6661937 | 0.75 | PCSK9 (0.53) | LPLLIPGPCSK9DRD2DRD3 | |
| Water SCHEMBL28757872 | 0.73 | MAOA (0.48) | MAOAMAOBSIGMAR1 | |
| SCHEMBL28275035 | 0.73 | SIGMAR1 (0.50) | MAOAMAOBSIGMAR1 | |
| SCHEMBL14085646 | 0.73 | PCSK9 (0.52) | PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |