Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783302 | 0.69 | CYP17A1 (0.33) | IDO1TAAR1CYP17A1CYP3A4 | |
| SCHEMBL9783313 | 0.63 | MEN1 (0.33) | CYP19A1 | |
| SCHEMBL9783783 | 0.62 | CYP19A1 (0.48) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL8939752 | 0.59 | ADRA1D (0.42) | ADRA1DADRA1AADRA1B | |
| SCHEMBL2741613 | 0.59 | ADRA1A (0.59) | HRH3IDO1TAAR1HRH4ADRA1D | |
| SCHEMBL9783702 | 0.59 | CYP19A1 (0.55) | CYP19A1TAAR1CYP17A1CYP3A4HRH4 | |
| SCHEMBL9783769 | 0.59 | PCSK9 (0.40) | HRH3IDO1CYP19A1TAAR1CYP17A1 | |
| SCHEMBL9783013 | 0.58 | CYP17A1 (0.41) | IDO1CYP19A1TAAR1CYP17A1CYP3A4 | |
| SCHEMBL2536900 | 0.58 | HRH3 (0.93) | HRH3TAAR1HRH4 | |
| SCHEMBL19223063 | 0.57 | ADRA1D (0.43) | TAAR1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |