Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783945 | 0.87 | CYP19A1 (0.43) | ALDH1A1P2RX7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9783707 | 0.80 | KCNA5 (0.37) | P2RX7KCNA5KCNH2CYP3A4ALOX15 | |
| SCHEMBL9783969 | 0.78 | P2RX7 (0.40) | ALDH1A1P2RX7IDH2CYP1A2CYP3A4 | |
| SCHEMBL9783248 | 0.78 | ALOX15 (0.42) | ALDH1A1P2RX7IDH2CYP1A2CYP3A4 | |
| SCHEMBL9783230 | 0.76 | ALOX15 (0.38) | ALDH1A1P2RX7IDH2CYP1A2CYP3A4 | |
| SCHEMBL9783176 | 0.74 | ALDH1A1 (0.40) | ALDH1A1P2RX7IDH2CYP1A2CYP3A4 | |
| SCHEMBL9783974 | 0.73 | KCNA5 (0.37) | ALDH1A1KCNA5KCNH2CYP1A2CYP3A4 | |
| SCHEMBL9783371 | 0.69 | CYP3A4 (0.42) | CYP3A4MEN1LMNAMAPTKMT2A | |
| SCHEMBL9783072 | 0.69 | IDO1 (0.39) | ALDH1A1P2RX7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9783926 | 0.69 | P2RX7 (0.42) | ALDH1A1P2RX7CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |