Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785366 | 0.83 | FOS (0.40) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL3564942 | 0.79 | CYP2C9 (0.47) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL10654101 | 0.78 | TDP1 (0.33) | ALDH1A1PKMKMT2A | |
| SCHEMBL9785488 | 0.77 | KDM4E (0.32) | ALDH1A1KDM4E | |
| SCHEMBL29117925 | 0.70 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERAB9AHPGD | |
| SCHEMBL9785541 | 0.70 | SMN1; SMN2 (0.45) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL31292519 | 0.69 | CNR2 (0.38) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL8950028 | 0.68 | SMN1; SMN2 (0.51) | ALDH1A1MAPTHPGDGAAMEN1 | |
| SCHEMBL10414576 | 0.68 | CA12 (0.54) | MAPTRAB9ANPC1 | |
| SCHEMBL10414574 | 0.68 | CA12 (0.54) | MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010200-A | Insecticide intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-23 | — | — | US | disclosed |
| US-4962109-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | disclosed |
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | disclosed |