Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785451 | 0.78 | FOS (0.38) | ALDH1A1PKMKMT2A | |
| SCHEMBL10654105 | 0.76 | GCK (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL9785488 | 0.68 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL4595467 | 0.62 | MAPK1 (0.52) | TDP1ALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL4202389 | 0.62 | TSHR (0.44) | TDP1MAOBALDH1A1PKMKMT2A | |
| SCHEMBL29577269 | 0.62 | TSHR (0.44) | TDP1MAOBALDH1A1PKMKMT2A | |
| SCHEMBL648491 | 0.62 | IDO1 (0.44) | TDP1ALDH1A1KMT2A | |
| SCHEMBL22778456 | 0.61 | RXRA (0.33) | — | |
| SCHEMBL5255523 | 0.61 | ALDH1A1 (0.65) | ALDH1A1PKMKMT2APOLB | |
| SCHEMBL1493636 | 0.60 | TDP1 (0.43) | TDP1MAOBMAOAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | disclosed |