Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786546 | 0.85 | NOTUM (0.54) | ALDH1A1NOTUMMEN1LMNAKMT2A | |
| SCHEMBL9786552 | 0.80 | PTGS2 (0.56) | TSHR | |
| SCHEMBL11331314 | 0.80 | NR1H4 (0.72) | ALDH1A1NOTUMMEN1LMNAKMT2A | |
| SCHEMBL11335546 | 0.77 | NR1H4 (0.54) | ALDH1A1NOTUMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13754330 | 0.77 | NOTUM (0.63) | ALDH1A1NOTUMLMNASMN1; SMN2MAPT | |
| SCHEMBL11342404 | 0.76 | RAB9A (0.48) | ALDH1A1NOTUMMEN1LMNAKMT2A | |
| SCHEMBL9016307 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1NOTUMMEN1LMNAKMT2A | |
| SCHEMBL5857932 | 0.75 | ALDH1A1 (0.58) | ALDH1A1NOTUMMEN1LMNAKMT2A | |
| SCHEMBL23566220 | 0.75 | CNR2 (0.48) | ALDH1A1NOTUMMEN1LMNAKMT2A | |
| SCHEMBL14226118 | 0.74 | ALDH1A1 (0.71) | ALDH1A1NOTUMLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524841-B2 | 4,4-disubstituted piperidine derivatives having CCR3 antagonism | TEIJIN LIMITED (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7524841-B2 | 4,4-disubstituted piperidine derivatives having CCR3 antagonism | TEIJIN LIMITED (JP) | 2009-04-28 | — | — | US | disclosed |
| US-7517875-B2 | Piperidine derivatives having CCR3 antagonism | TEIJIN LIMITED (JP) | 2009-04-14 | — | — | US | disclosed |
| US-7517875-B2 | Piperidine derivatives having CCR3 antagonism | TEIJIN LIMITED (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20070037851-A1 | Inhibits binding of CCR3 ligands such as eotaxins to their target cells; inhibits physiological effects of binding; therapeutic and prophylactic agents for asthma, rhinitis, dermatitis, urticaria, conjunctivitis, inflammatory bowel; tissue infiltration of eosinophils, basophils, activated T cells | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-15 | — | — | US | disclosed |
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-08 | — | — | US | disclosed |
| US-4992347-A | Marking | COURTAULDS PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0190016-B1 | PHOTOCHROMIC 3-PYRRYL FULGIDES & FULGIMIDES | GEC-MARCONI LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0390869-A4 | ORGANIC PHOTOCHROMIC PIGMENT | — | 1990-11-07 | — | — | EP | disclosed |
| EP-0390869-A1 | ORGANIC PHOTOCHROMIC PIGMENT | PPG INDUSTRIES, INC. (US) | 1990-10-10 | — | — | EP | disclosed |
| US-4931220-A | EMULSION POLYMERIZATION OF POLYFUNCTIONAL ACRYLATE MIXED WITH PIGMENT; POWDERS | PPG INDUSTRIES, INC. (US) | 1990-06-05 | — | — | US | disclosed |
| WO-1989005464-A1 | ORGANIC PHOTOCHROMIC PIGMENT | PPG INDUSTRIES, INC. (US) | 1989-06-15 | — | — | WO | disclosed |
| EP-0279600-A1 | Marking | COURTAULDS PLC (GB) | 1988-08-24 | — | — | EP | disclosed |
| EP-0190016-A2 | Photochromic 3-pyrryl fulgides & fulgimides | GEC-MARCONI LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | CCR3, CCR1, CCR4 | ALDH1A1 451/4885NOTUM 2644/4885MEN1 3556/4885 |
| US-20070037851-A1 | Inhibits binding of CCR3 ligands such as eotaxins to their target cells; inhibits physiological effects of binding; therapeutic and prophylactic agents for asthma, rhinitis, dermatitis, urticaria, conjunctivitis, inflammatory bowel; tissue infiltration of eosinophils, basophils, activated T cells | CCR3, CCR1, CCR4 | ALDH1A1 486/4885NOTUM 3102/4885MEN1 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.