Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL9786967 | 0.89 | CES2 (0.54) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| SCHEMBL22778963 | 0.86 | ALDH1A1 (0.57) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| Phenol SCHEMBL11815882 | 0.85 | TDP1 (0.52) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| SCHEMBL862846 | 0.84 | HSD17B3 (0.58) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| SCHEMBL10545852 | 0.84 | ESR2 (0.56) | NPC1RAB9AALDH1A1MAPTTDP1 | |
| SCHEMBL863102 | 0.82 | ESR2 (0.59) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| SCHEMBL841978 | 0.81 | ESR2 (0.50) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| SCHEMBL28716695 | 0.80 | ALDH1A1 (0.46) | NPC1RAB9APTPN1ALDH1A1MAPT | |
| SCHEMBL11806422 | 0.79 | NPC1 (0.59) | NPC1RAB9AALDH1A1MAPTPOLB | |
| SCHEMBL866784 | 0.79 | GSK3B (0.61) | NPC1RAB9AMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029723-A1 | NOVEL PHOTOACTIVATABLE PACLITAXEL DERIVATIVES AND USES THEREOF, IN PARTICULAR IN CELLBIOLOGY AND CANCER TREATMENT | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2013-03-07 | — | — | WO | claimed |
| EP-2565188-A1 | Novel photoactivatable paclitaxel derivatives and uses thereof, in particular in cellbiology and cancer treatment | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-03-06 | — | — | EP | claimed |
| WO-2013029723-A1 | NOVEL PHOTOACTIVATABLE PACLITAXEL DERIVATIVES AND USES THEREOF, IN PARTICULAR IN CELLBIOLOGY AND CANCER TREATMENT | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013029723-A1 | NOVEL PHOTOACTIVATABLE PACLITAXEL DERIVATIVES AND USES THEREOF, IN PARTICULAR IN CELLBIOLOGY AND CANCER TREATMENT | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2013-03-07 | — | — | WO | disclosed |
| EP-2565188-A1 | Novel photoactivatable paclitaxel derivatives and uses thereof, in particular in cellbiology and cancer treatment | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-03-06 | — | — | EP | disclosed |
| EP-2565188-A1 | Novel photoactivatable paclitaxel derivatives and uses thereof, in particular in cellbiology and cancer treatment | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-03-06 | — | — | EP | disclosed |