Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878630 | 0.83 | PDE4A (0.48) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL10804269 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBMEN1TDP1 | |
| SCHEMBL181841 | 0.71 | ALDH1A1 (0.74) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL10803994 | 0.70 | IDO1 (0.42) | ALDH1A1KMT2ATDP1CES2CES1 | |
| SCHEMBL9787184 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL10806794 | 0.69 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL9787259 | 0.69 | HPGDS (0.45) | ALDH1A1KMT2APOLBMEN1CES2 | |
| SCHEMBL9787361 | 0.68 | PDE4A (0.45) | KMT2AMEN1CES2CES1HSD17B10 | |
| SCHEMBL9787252 | 0.68 | PDE4A (0.45) | ALDH1A1TDP1CES2CES1HSD17B10 | |
| SCHEMBL11061813 | 0.68 | POLB (0.45) | ALDH1A1KMT2APOLBMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999365-A | Preventing damage which occurs to heart tissue when oxygen is reintroduced after a heart attack | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-03-12 | — | — | US | disclosed |