Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 8/20 | 0.45 |
| ▸ | SELE | P16581 | 7/20 | 0.45 |
| ▸ | SELL | P14151 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FUT4 | P22083 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383712 | 0.81 | IAPP (0.57) | MAPTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL5423386 | 0.81 | PTGS1 (0.43) | SELPSELESELLCA1CA2 | |
| SCHEMBL490873 | 0.79 | KEAP1 (0.52) | SELPSELESELLMAPTKDM4E | |
| SCHEMBL5929237 | 0.78 | TRPA1 (0.52) | MAPTCA1CA2LMNAGAA | |
| SCHEMBL5421780 | 0.78 | GAA (0.59) | MAPTALDH1A1LMNATP53MAPK1 | |
| SCHEMBL5929236 | 0.78 | PTPN1 (0.38) | MAPTLMNAIAPPL3MBTL1GAA | |
| SCHEMBL1137129 | 0.74 | ESR1 (0.50) | MAPTKDM4EALDH1A1CA2LMNA | |
| SCHEMBL9159296 | 0.74 | LCK (0.63) | KDM4ECA12ALDH1A1CA1CA2 | |
| SCHEMBL31218542 | 0.74 | NPC1 (0.41) | SELPSELESELLHPGDMAPK1 | |
| SCHEMBL30529 | 0.74 | KEAP1 (0.61) | MAPTALDH1A1MAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030666-A | Shell-core polymers; adhesives, coatings | ROHM AND HAAS COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4791151-A | Multilobals | ROHM AND HAAS COMPANY (US) | 1988-12-13 | — | — | US | disclosed |