Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787734 | 0.81 | ESRRG (0.49) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL9439608 | 0.71 | KMT2A (0.53) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7181443 | 0.71 | KMT2A (0.40) | KMT2AMEN1L3MBTL1TAAR1ACACB | |
| SCHEMBL9787733 | 0.69 | KMT2A (0.64) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| Acetic Acid SCHEMBL9787824 | 0.68 | NPC1 (0.48) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL9787705 | 0.68 | SMN1; SMN2 (0.45) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL9787729 | 0.68 | KMT2A (0.53) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7188859 | 0.67 | LMNA (0.41) | KMT2AMEN1MAPTL3MBTL1TAAR1 | |
| SCHEMBL7183985 | 0.66 | L3MBTL1 (0.38) | KMT2AMEN1MAPTL3MBTL1TAAR1 | |
| SCHEMBL9439602 | 0.65 | SMN1; SMN2 (0.52) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |