Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524018 | 0.86 | BCL9 (0.58) | BCL9CTNNB1ESR1KMT2ALMNA | |
| SCHEMBL7484158 | 0.86 | BCL9 (0.58) | BCL9CTNNB1ESR1KMT2ALMNA | |
| SCHEMBL20703605 | 0.84 | BCL9 (0.60) | BCL9CTNNB1ESR1KMT2ALMNA | |
| SCHEMBL11023644 | 0.82 | BCL9 (0.70) | BCL9CTNNB1ESR1KMT2ALMNA | |
| SCHEMBL10432965 | 0.82 | TP53 (0.61) | LMNARARBSMN1; SMN2 | |
| SCHEMBL8765721 | 0.79 | BCL9 (0.62) | BCL9CTNNB1ESR1KMT2ALMNA | |
| SCHEMBL30122612 | 0.79 | L3MBTL1 (0.54) | LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL4061378 | 0.78 | NQO1 (0.57) | THRAKMT2ALMNAALDH1A1RARB | |
| SCHEMBL4056036 | 0.78 | LMNA (0.56) | THRAKMT2ALMNAMAPTRARB | |
| SCHEMBL4732 | 0.78 | BCL9 (0.60) | BCL9CTNNB1ESR1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |