Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788244 | 0.92 | NR4A3 (0.53) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL9788273 | 0.89 | NR4A3 (0.67) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL9005800 | 0.88 | MAPT (0.51) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL9788330 | 0.86 | NR4A3 (0.42) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL9788277 | 0.86 | NR4A3 (0.41) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL9788295 | 0.82 | LMNA (0.43) | NR4A3ALDH1A1MAPTGAAMAPK14 | |
| SCHEMBL9788337 | 0.82 | NR4A3 (0.50) | NR4A3ALDH1A1MAPTMAPK1MAPK14 | |
| SCHEMBL773204 | 0.81 | NR4A3 (0.78) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL9788265 | 0.81 | NR4A3 (0.41) | NR4A3ALDH1A1MAPTMAPK1GAA | |
| SCHEMBL10813419 | 0.81 | RAB9A (0.46) | NR4A3ALDH1A1MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |