Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788244 | 0.89 | NR4A3 (0.53) | NR4A3MAPK14MAPTAGTR1LMNA | |
| SCHEMBL10813419 | 0.88 | RAB9A (0.46) | NR4A3MAPK14MAPTLMNAL3MBTL1 | |
| SCHEMBL9788322 | 0.81 | ALDH1A1 (0.43) | NR4A3MAPK14MAPTAGTR1LMNA | |
| SCHEMBL9788253 | 0.81 | NR4A3 (0.56) | NR4A3MAPK14MAPTLMNAALDH1A1 | |
| SCHEMBL9005800 | 0.80 | MAPT (0.51) | NR4A3MAPK14MAPTLMNANPSR1 | |
| SCHEMBL10357762 | 0.80 | POLB (0.38) | AGTR1PPARAALDH1A1POLBKDM4E | |
| SCHEMBL9788277 | 0.78 | NR4A3 (0.41) | NR4A3MAPK14MAPTLMNAALDH1A1 | |
| SCHEMBL9788326 | 0.77 | MAPK14 (0.45) | NR4A3MAPK14LMNA | |
| SCHEMBL9788315 | 0.76 | AGTR1 (0.40) | NR4A3MAPTAGTR1LMNAL3MBTL1 | |
| SCHEMBL9005834 | 0.76 | NR4A3 (0.52) | NR4A3MAPTL3MBTL1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |