Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715183 | 0.82 | HCAR1 (0.36) | HCAR1EPRS1RBP4MEN1KMT2A | |
| SCHEMBL9458510 | 0.78 | NR4A3 (0.51) | NR4A3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9788353 | 0.76 | CRHBP (0.38) | NR4A3NPC1RAB9AMAPT | |
| SCHEMBL9788349 | 0.72 | LMNA (0.47) | HCAR1RAB9AMYCNR4A1MAPT | |
| SCHEMBL9005789 | 0.72 | NR4A3 (0.47) | NR4A3MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9788296 | 0.71 | NR4A3 (0.46) | NR4A3MEN1KMT2APOLB | |
| SCHEMBL9788273 | 0.71 | NR4A3 (0.67) | NR4A3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9005834 | 0.69 | NR4A3 (0.52) | NR4A3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL122191 | 0.68 | NR4A3 (0.51) | NR4A3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9005822 | 0.68 | NR4A3 (0.51) | NR4A3KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |