Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357416 | 0.81 | LMNA (0.52) | LMNAHCAR1SCN9ANR3C2MAPT | |
| SCHEMBL10366872 | 0.77 | SMN1; SMN2 (0.44) | HCAR1SCN9ANR3C2MAPTSMN1; SMN2 | |
| SCHEMBL9005750 | 0.76 | KMT2A (0.48) | LMNASMN1; SMN2RAB9ANOTUMNPSR1 | |
| SCHEMBL9788261 | 0.75 | KMT2A (0.51) | LMNASMN1; SMN2RAB9ANOTUMKDM4E | |
| SCHEMBL10365970 | 0.75 | SCN9A (0.48) | HCAR1SCN9AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9788260 | 0.73 | HIF1A (0.44) | LMNAMAPTSMN1; SMN2KDM4ECCR1 | |
| SCHEMBL10365987 | 0.72 | MEN1 (0.40) | HCAR1SCN9AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9788258 | 0.72 | HCAR1 (0.37) | HCAR1MAPTSMN1; SMN2TP53RAB9A | |
| SCHEMBL2298539 | 0.70 | POLB (0.54) | LMNASCN9AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2900510 | 0.70 | HCAR1 (0.42) | HCAR1SCN9ANR3C2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |