Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788240 | 0.86 | MAPK1 (0.58) | KMT2AHTTPKMNPC1RAB9A | |
| SCHEMBL9005750 | 0.85 | KMT2A (0.48) | KMT2AALDH1A1NOTUMNPC1RAB9A | |
| SCHEMBL9005822 | 0.83 | NR4A3 (0.51) | KMT2AHTTALDH1A1KDM4EPKM | |
| SCHEMBL6052435 | 0.82 | KMT2A (0.64) | KMT2AHTTPKMNOTUMNPC1 | |
| SCHEMBL2201890 | 0.79 | LMNA (0.64) | KMT2AALDH1A1KDM4EPKMNOTUM | |
| SCHEMBL10357500 | 0.77 | ALDH1A1 (0.59) | KMT2AALDH1A1KDM4EPKMNOTUM | |
| SCHEMBL18933554 | 0.76 | RXRA (0.52) | KMT2AHTTALDH1A1PKMNPC1 | |
| SCHEMBL6345488 | 0.76 | MAPK1 (0.70) | KMT2AHTTALDH1A1PKMNPC1 | |
| SCHEMBL9788349 | 0.75 | LMNA (0.47) | HTTKDM4ENOTUMRAB9ALMNA | |
| SCHEMBL11624685 | 0.75 | NOTUM (0.68) | KMT2AALDH1A1KDM4EPKMNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |