Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788323 | 0.90 | CYP1A2 (0.55) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL9788262 | 0.90 | LMNA (0.48) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL9788240 | 0.79 | MAPK1 (0.58) | CYP2C9CYP2C19CYP1A2MEN1KMT2A | |
| SCHEMBL10812124 | 0.79 | SRC (0.44) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL4497271 | 0.79 | ALDH1A1 (0.65) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL9788273 | 0.76 | NR4A3 (0.67) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10816206 | 0.76 | LMNA (0.44) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL9788337 | 0.75 | NR4A3 (0.50) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4494401 | 0.74 | CYP2C9 (0.69) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL10357411 | 0.74 | CYP2C9 (0.64) | CYP2C9CYP2C19CYP1A2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |