Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828627 | 0.74 | TNKS (0.45) | TNKSGRM5L3MBTL1SPTLC1LMNA | |
| SCHEMBL454081 | 0.74 | SPTLC1 (0.53) | TNKSMAPTL3MBTL1SPTLC1HDAC6 | |
| SCHEMBL1349074 | 0.73 | L3MBTL1 (0.49) | TNKSCYP1A2METAP2L3MBTL1HDAC6 | |
| SCHEMBL30256773 | 0.72 | GRM5 (0.43) | TNKSCYP1A2METAP2GRM5NPC1 | |
| SCHEMBL12241175 | 0.72 | SCN10A (0.44) | MCHR1RAF1BRAF | |
| SCHEMBL20125121 | 0.72 | ACKR3 (0.43) | TNKSNPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL1346286 | 0.71 | MCHR1 (0.44) | TNKSCYP1A2METAP2GRM5NPC1 | |
| SCHEMBL3340580 | 0.71 | SMN1; SMN2 (0.49) | CYP1A2GRM5NPC1RAB9ACYP3A4 | |
| SCHEMBL1431759 | 0.71 | TNKS (0.47) | TNKSNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL1346289 | 0.70 | MCHR1 (0.45) | TNKSCYP1A2METAP2GRM5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990506-A | Sedatives, anxiolytic, antiulcer, antistress | SYNTHELABO (FR) | 1991-02-05 | — | — | US | disclosed |