Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828627 | 0.80 | TNKS (0.45) | L3MBTL1TNKSCDK5CDK5R1ALDH1A2 | |
| SCHEMBL20801724 | 0.80 | METAP2 (0.40) | L3MBTL1CDK5CDK5R1ALDH1A2ALDH1A3 | |
| SCHEMBL12920738 | 0.75 | MAPT (0.48) | L3MBTL1CDK5CDK5R1ALDH1A2ALDH1A3 | |
| SCHEMBL1367213 | 0.75 | GRM4 (0.45) | CDK2NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL13325790 | 0.74 | ALDH1A3 (0.59) | CDK5CDK5R1ALDH1A2ALDH1A3ADORA2A | |
| SCHEMBL4672079 | 0.74 | ALDH1A3 (0.54) | ALDH1A2ALDH1A3CDK2CCNE1NPC1 | |
| SCHEMBL454081 | 0.74 | SPTLC1 (0.53) | L3MBTL1TNKSSPTLC1SMN1; SMN2KDM4E | |
| SCHEMBL2260742 | 0.73 | L3MBTL1 (0.67) | ACKR3L3MBTL1TNKSNPC1RAB9A | |
| SCHEMBL13821670 | 0.72 | L3MBTL1 (0.50) | ACKR3L3MBTL1TNKSADORA2AKDM4E | |
| SCHEMBL9788686 | 0.72 | TNKS (0.46) | L3MBTL1TNKSSPTLC1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |