Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9788976

CC(C)(N)c1ccc(O)c(C(C)(C)N)c1C(C)(C)N.N

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.34
ALOX15 P16050 4/20 0.34
HSD17B10 Q99714 3/20 0.34
NR1I2 O75469 1/20 0.34
LMNA P02545 1/20 0.34
CYP2C9 P11712 1/20 0.34
MIF P14174 1/20 0.34
TYR P14679 1/20 0.34
HTT P42858 1/20 0.34
NFE2L2 Q16236 1/20 0.34
MAPT P10636 3/20 0.32
MEN1 O00255 2/20 0.32
GAA P10253 2/20 0.32
RECQL P46063 2/20 0.32
KMT2A Q03164 2/20 0.32
PKM P14618 1/20 0.32
TDP1 Q9NUW8 3/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 2/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33426 0.98 ALDH1A1 (0.35) ALDH1A1ALOX15HSD17B10NR1I2LMNA
Alcohol SCHEMBL8950695 0.90 KLF10 (0.32) ALDH1A1ALOX15HSD17B10NR1I2LMNA
Piperazine SCHEMBL10545719 0.87
Phenol SCHEMBL10456859 0.87 TDP1 (0.39) ALDH1A1ALOX15HSD17B10NR1I2LMNA
SCHEMBL2173229 0.78 ALDH1A1 (0.46) ALDH1A1ALOX15HSD17B10NR1I2LMNA
SCHEMBL14698448 0.73
SCHEMBL16728382 0.69 CA2 (0.40) ALDH1A1TDP1TSHR
Ammonia Solution, Strong SCHEMBL478297 0.68 ALDH1A1 (0.46) ALDH1A1ALOX15HSD17B10NR1I2LMNA
SCHEMBL8392134 0.68 CYP3A4 (0.48) ALDH1A1ALOX15HSD17B10MAPTMEN1
SCHEMBL4659703 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230112-A2 Fluor-containing epoxy fluorocarbon coating composition and process for making the same THE STANDARD OIL COMPANY (US) 1987-07-29 EP claimed
US-5075378-A Coating of an epoxy resin, fluorocarbon polymer fluorinated curing agent THE STANDARD OIL COMPANY (US) 1991-12-24 US disclosed
EP-0230112-B1 FLUOR-CONTAINING EPOXY FLUOROCARBON COATING COMPOSITION AND PROCESS FOR MAKING THE SAME THE STANDARD OIL COMPANY (US) 1990-05-02 EP disclosed
EP-0230112-A2 Fluor-containing epoxy fluorocarbon coating composition and process for making the same THE STANDARD OIL COMPANY (US) 1987-07-29 EP disclosed