Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16728382 | 0.84 | CA2 (0.40) | ALDH1A1TDP1TSHRCA2GABRA1 | |
| SCHEMBL33426 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TDP1TSHRCA2ALOX15 | |
| SCHEMBL10692638 | 0.80 | CA2 (0.50) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL30626639 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL141506 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| Ammonia Solution, Strong SCHEMBL9788976 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TDP1TSHRALOX15LMNA | |
| SCHEMBL8388477 | 0.77 | TSHR (0.46) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL7848673 | 0.77 | TRPA1 (0.37) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL1698713 | 0.77 | CA2 (0.64) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL10619689 | 0.76 | GABRA1 (0.43) | ALDH1A1TDP1TSHRCA2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845830-B2 | Method for producing a composition comprising a polyurethane with NCO end groups | BOSTIK SA (FR) | 2023-12-19 | — | — | US | claimed |
| US-20220018078-A1 | Composite System and Method for Pile Construction and Repair | SZCZEPANIAK ZBIGNIEW ANDREW (US) | 2022-01-20 | — | — | US | claimed |
| US-10899986-B2 | Substituted Mannich base fuel additives, compositions, and methods | EVONIK OPERATIONS GMBH (DE) | 2021-01-26 | — | — | US | claimed |
| US-20200308337-A1 | METHOD FOR PRODUCING A COMPOSITION COMPRISING A POLYURETHANE WITH NCO END GROUPS | BOSTIK SA (FR) | 2020-10-01 | — | — | US | claimed |
| US-10676564-B2 | Amidoamine and polyamide curing agents, compositions, and methods | EVONIK OPERATIONS GMBH (DE) | 2020-06-09 | — | — | US | claimed |
| EP-3504303-B1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2020-04-01 | — | — | EP | claimed |
| EP-3411421-B1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2019-12-25 | — | — | EP | claimed |
| EP-3504303-A1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | Evonik Degussa GmbH (DE) | 2019-07-03 | — | — | EP | claimed |
| US-20190169515-A1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2019-06-06 | — | — | US | claimed |
| EP-3411421-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | Evonik Degussa GmbH (DE) | 2018-12-12 | — | — | EP | claimed |
| US-20170218115-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2017-08-03 | — | — | US | claimed |
| US-9334409-B2 | Curing agent for low temperature cure applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-05-10 | — | — | US | claimed |
| EP-2726531-B1 | CURABLE EPOXY RESIN SYSTEMS CONTAINING MIXTURES OF AMINE HARDENERS AND AN EXCESS OF EPOXIDE GROUPS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-07-22 | — | — | EP | claimed |
| US-20140256853-A1 | Curing Agent for Low Temperature Cure Applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-11 | — | — | US | claimed |
| EP-2726531-A1 | CURABLE EPOXY RESIN SYSTEMS CONTAINING MIXTURES OF AMINE HARDENERS AND AN EXCESS OF EPOXIDE GROUPS | Dow Global Technologies LLC (US) | 2014-05-07 | — | — | EP | claimed |
| US-8513376-B2 | Polyamides and amidoamines from selectively modified amine amines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-08-20 | — | — | US | claimed |
| WO-2013003202-A1 | CURABLE EPOXY RESIN SYSTEMS CONTAINING MIXTURES OF AMINE HARDENERS AND AN EXCESS OF EPOXIDE GROUPS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-01-03 | — | — | WO | claimed |
| US-8293863-B2 | comprising the reaction product of multifunctional amines such as N,N-bis(3-aminopropyl) ethylenediamine, with dimer fatty acids or esters, useful for crosslinking epoxy resins to produce quick-drying coatings, adhesives, floors and composites | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2012-10-23 | — | — | US | claimed |
| US-20090259003-A1 | Curing Agent For Low Temperature Cure Applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-10-15 | — | — | US | claimed |
| EP-2108668-A1 | Curing agent for low temperature cure applications | Air Products and Chemicals, Inc. (US) | 2009-10-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256853-A1 | Curing Agent for Low Temperature Cure Applications | PNMT, PAM, HNMT | ALDH1A1 727/4885TDP1 2175/4885TSHR 4743/4885 |
| US-10899986-B2 | Substituted Mannich base fuel additives, compositions, and methods | H1-2, H1-0, H1-3 | ALDH1A1 126/4885TDP1 1691/4885TSHR 4360/4885 |
| US-10676564-B2 | Amidoamine and polyamide curing agents, compositions, and methods | NAAA, FAAH2, H1-2 | ALDH1A1 1227/4885TDP1 1549/4885TSHR 2952/4885 |
| US-20090259003-A1 | Curing Agent For Low Temperature Cure Applications | PNMT, PAM, HNMT | ALDH1A1 727/4885TDP1 2175/4885TSHR 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.