Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9789638 | 0.74 | ALDH1A1 (0.43) | MAOBALDH1A1MAOAALPGPLAA | |
| SCHEMBL9618120 | 0.72 | MAOB (0.60) | MAOBCYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL9789640 | 0.71 | CYP11B1 (0.39) | MAOBCYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL11639718 | 0.68 | MAOB (0.51) | MAOBALDH1A1MAOASMN1; SMN2PTPN1 | |
| SCHEMBL12655257 | 0.66 | MAOB (0.73) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL8786734 | 0.65 | MAOB (0.51) | MAOBCYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL11394273 | 0.65 | MAOB (0.51) | MAOBCYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL11405457 | 0.64 | PTGS2 (0.50) | MAOBCYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL8787868 | 0.64 | KDM4E (0.51) | MAOBCYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL11390180 | 0.63 | MAOB (0.46) | MAOBALDH1A1MAOASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3291280-A | — | — | None | — | — | JP | disclosed |
| JP-H03291280-A | THIOCHROMONE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1991-12-20 | — | — | JP | disclosed |