SCHEMBL9790758

SCHEMBL9790758

O=P(O)(O)C(Nc1ncns1)P(=O)(O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FDPS P14324 16/20 0.54
FDFT1 P37268 2/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP2 P08253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7165656 0.70 FDPS (1.00) FDPS
SCHEMBL24255877 0.70
SCHEMBL9790607 0.69 FDPS (0.96) FDPS
SCHEMBL9790803 0.68 FDPS (0.66) FDPSFDFT1
SCHEMBL7164309 0.68 FDPS (1.00) FDPSCA12CA1
SCHEMBL9790756 0.67 FDPS (0.97) FDPSCA12CA1
SCHEMBL9790600 0.67 FDPS (0.54) FDPSCA12CA9CA1CA2
SCHEMBL9790652 0.66 FDPS (1.00) FDPSFDFT1
SCHEMBL7945367 0.65 FDPS (1.00) FDPSFDFT1CA12CA1
SCHEMBL9790635 0.64 FDPS (1.00) FDPSFDFT1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057505-A Treatment of illnesses attributed to calcium metabolism disorders CIBA-GEIGY CORPORATION (US) 1991-10-15 US disclosed