Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790706 | 0.70 | FDPS (0.50) | CA12CA9MMP2FDPSFDFT1 | |
| SCHEMBL9790744 | 0.69 | FDPS (0.49) | CA12CA9MMP2FDPSFDFT1 | |
| SCHEMBL10337554 | 0.64 | FDPS (0.49) | CA12CA1FDPSMMP8FDFT1 | |
| SCHEMBL9790674 | 0.63 | FDPS (0.44) | CA12CA9MMP2CA1CA2 | |
| SCHEMBL9790600 | 0.63 | FDPS (0.54) | CA12CA9MMP2CA1CA2 | |
| SCHEMBL17187151 | 0.62 | MMP2 (0.83) | CA12CA9MMP2CA1CA2 | |
| SCHEMBL9790605 | 0.61 | NPC1 (0.51) | CA12CA9MMP2CA2FDPS | |
| SCHEMBL9790750 | 0.61 | FDPS (0.41) | FDPSFDFT1 | |
| SCHEMBL7797073 | 0.60 | FDPS (0.61) | CA12CA9FDPSMMP8MMP14 | |
| SCHEMBL8974849 | 0.59 | FDPS (0.50) | CA12CA9MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |