Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | HINT1 | P49773 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534659 | 0.90 | KDM4E (0.49) | ALDH1A1POLA1TAS1R3TAS1R1KDM4E | |
| SCHEMBL2113125 | 0.90 | KDM4E (0.49) | ALDH1A1POLA1TAS1R3TAS1R1KDM4E | |
| SCHEMBL2113415 | 0.89 | TAS1R3 (0.40) | ALDH1A1MEN1KMT2APOLA1TAS1R3 | |
| SCHEMBL9801846 | 0.87 | TYMP (0.41) | POLA1TAS1R3TAS1R1KDM4ETYMP | |
| SCHEMBL32677371 | 0.85 | TYMP (0.58) | ALDH1A1MEN1KMT2APOLA1TAS1R3 | |
| SCHEMBL8574965 | 0.84 | HPGD (0.46) | TYMPHINT1TAAR1HPGD | |
| SCHEMBL4553693 | 0.82 | KDM4E (0.51) | ALDH1A1MEN1KMT2APOLA1TAS1R3 | |
| SCHEMBL9548725 | 0.81 | TYMP (0.58) | ALDH1A1TYMPLMNAMAPT | |
| SCHEMBL2113123 | 0.81 | KDM4E (0.50) | ALDH1A1MEN1KMT2APOLA1TAS1R3 | |
| SCHEMBL2115347 | 0.80 | TAS1R3 (0.54) | TAS1R3TAS1R1TYMPHINT1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043430-A | Process for treating insoluble heterologous protein | TOSOH CORPORATION (JP) | 1991-08-27 | — | — | US | disclosed |