Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113125 | 0.89 | KDM4E (0.49) | TYMPPOLA1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL7534659 | 0.89 | KDM4E (0.49) | TYMPPOLA1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL9790905 | 0.87 | ALDH1A1 (0.44) | TYMPPOLA1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL8574965 | 0.86 | HPGD (0.46) | TYMPTAAR1HPGDPOLBP2RY2 | |
| SCHEMBL2113415 | 0.86 | TAS1R3 (0.40) | TYMPPOLA1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL22983970 | 0.85 | TYMP (0.60) | TYMPPOLA1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL8326666 | 0.85 | TYMP (0.60) | TYMPPOLA1KDM4ETAS1R3TAS1R1 | |
| SCHEMBL9548725 | 0.82 | TYMP (0.58) | TYMP | |
| SCHEMBL2270354 | 0.80 | POLB (0.38) | TYMPPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL4553693 | 0.80 | KDM4E (0.51) | TYMPPOLA1KDM4ETAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115613-B1 | DNA SEQUENCES, THEIR PREPARATION, PLASMIDS CONTAINING THESE SEQUENCES AND THEIR USE IN THE SYNTHESIS OF EUKARYOTIC GENE PRODUCTS IN PROKARYOTES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1991-03-27 | — | — | EP | disclosed |
| EP-0115613-A2 | DNA sequences, their preparation, plasmids containing these sequences and their use in the synthesis of eukaryotic gene products in prokaryotes | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1984-08-15 | — | — | EP | disclosed |