Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | CHIA | Q9BZP6 | 4/20 | 0.49 |
| ▸ | CHIT1 | Q13231 | 3/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455907 | 0.82 | GAA (0.69) | GAAMAPTALDH1A1GFERCHIA | |
| SCHEMBL9793471 | 0.80 | GAA (0.67) | GAAMAPTALDH1A1GFERCHIA | |
| SCHEMBL1994355 | 0.77 | GAA (1.00) | GAAMAPTALDH1A1GFERCHIA | |
| SCHEMBL31387185 | 0.72 | GAA (0.56) | GAAMAPTALDH1A1GFERCHIA | |
| SCHEMBL27082996 | 0.71 | HRH4 (0.59) | HRH4KMT2A | |
| SCHEMBL5032275 | 0.71 | HRH4 (0.78) | HRH4 | |
| SCHEMBL20628967 | 0.70 | CHIT1 (0.60) | GAAMAPTALDH1A1GFERCHIA | |
| SCHEMBL31214493 | 0.70 | GAA (0.63) | GAAMAPTALDH1A1GFERCHIA | |
| SCHEMBL26037956 | 0.68 | HRH4 (0.61) | HRH4KMT2A | |
| SCHEMBL19127856 | 0.67 | HTR1D (0.39) | GAACHIACHIT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064826-A | Analgesic, antiderpressant | EGIS GYOGYSZERGYAR (HU) | 1991-11-12 | — | — | US | disclosed |