Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676590 | 0.81 | ENPP1 (0.48) | KDM4ETDP1ADORA2AADORA1ADORA2B | |
| SCHEMBL18264128 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL30774158 | 0.81 | ALDH1A1 (0.37) | KDM4EADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL30774201 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL30950214 | 0.81 | ENPP1 (0.48) | KDM4ETDP1ADORA2AADORA1ADORA2B | |
| SCHEMBL24373483 | 0.81 | ALDH1A1 (0.37) | KDM4EADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL29479071 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL24373525 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9794585 | 0.76 | MEN1 (0.34) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL9794613 | 0.75 | ALDH1A1 (0.47) | KDM4ETDP1ALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252350-B1 | 3-CYANOQUINOLINE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-01-02 | — | — | EP | disclosed |
| EP-0252350-A1 | 3-Cyanoquinoline derivatives | BASF Aktiengesellschaft (DE) | 1988-01-13 | — | — | EP | disclosed |