Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533903 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL9794635 | 0.75 | CTSB (0.46) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL9794601 | 0.75 | TDP1 (0.42) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL30950214 | 0.75 | ENPP1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL28676590 | 0.75 | ENPP1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL24373483 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4EPDE10A | |
| SCHEMBL9794609 | 0.75 | KDM4E (0.39) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL30774201 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30774158 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4EPDE10A | |
| SCHEMBL18264128 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252350-B1 | 3-CYANOQUINOLINE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-01-02 | — | — | EP | disclosed |
| EP-0252350-A1 | 3-Cyanoquinoline derivatives | BASF Aktiengesellschaft (DE) | 1988-01-13 | — | — | EP | disclosed |