Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | OGA | O60502 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794819 | 0.93 | L3MBTL1 (0.47) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL4472290 | 0.86 | L3MBTL1 (0.54) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL3511935 | 0.86 | L3MBTL1 (0.54) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL4469579 | 0.84 | SMN1; SMN2 (0.53) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL3551633 | 0.77 | ALDH1A1 (0.49) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL9794803 | 0.75 | BAZ2A (0.48) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL1713003 | 0.75 | L3MBTL1 (0.47) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL6929063 | 0.75 | ALDH1A1 (0.54) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL2228747 | 0.74 | BAZ2A (0.49) | L3MBTL1MEN1HRH3DPP4SMN1; SMN2 | |
| SCHEMBL4463690 | 0.74 | LMNA (0.68) | MEN1SMN1; SMN2ARLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | claimed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | claimed |
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| EP-0338352-A3 | SALICYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |