Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49520 | 0.79 | TSHR (0.48) | ALDH1A1EPHX1MAPTSMN1; SMN2HPGD | |
| SCHEMBL17273060 | 0.73 | TSHR (0.34) | KCNH3ALDH1A1NPSR1GAAMAPT | |
| SCHEMBL10788267 | 0.71 | EPHX1 (0.42) | KCNH3ALDH1A1NPSR1EPHX1HTT | |
| Phenol SCHEMBL1561461 | 0.70 | CA12 (0.50) | ALDH1A1MAPTHPGDLMNAHSD17B10 | |
| SCHEMBL11097238 | 0.67 | TSHR (0.40) | ALDH1A1NPSR1GAAMAPTHPGD | |
| SCHEMBL9850860 | 0.66 | KMT2A (0.41) | KCNH3ALDH1A1NPSR1EPHX1HTT | |
| SCHEMBL9181403 | 0.65 | TSHR (0.48) | ALDH1A1EPHX1MAPTSMN1; SMN2HPGD | |
| SCHEMBL717181 | 0.65 | TSHR (0.48) | ALDH1A1EPHX1HTTMAPTSMN1; SMN2 | |
| SCHEMBL10787743 | 0.65 | TSHR (0.42) | ALDH1A1NPSR1GAAMAPTHPGD | |
| SCHEMBL10998222 | 0.65 | TSHR (0.42) | ALDH1A1NPSR1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036147-A | Coordination catalyst comprising a silica support, a magnesium silylamide, an electron donor and a titanium halide; stereospecific; hydrocarbon soluble | QUANTUM CHEMICAL CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0405554-A2 | Propylene polymerization catalyst and method | QUANTUM CHEMICAL CORPORATION (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4968653-A | COORDINATION CATALYST MADE FROM MAGNESIUM SILYLAMIDE | QUANTUM CHEMICAL CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |