Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9795135 | 0.92 | POLB (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAOA | |
| SCHEMBL9501486 | 0.86 | SMYD3 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9795170 | 0.86 | SMYD3 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9498706 | 0.86 | SMYD3 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9019581 | 0.83 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9137074 | 0.83 | SMYD3 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9130345 | 0.81 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL4191188 | 0.80 | MAOA (0.47) | ALDH1A1SMN1; SMN2MAOAMAPTNPSR1 | |
| SCHEMBL9127102 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT | |
| SCHEMBL9125633 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2BCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |