Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795202 | 0.87 | KMT2A (0.39) | HTTPOLBBCHELMNAALDH1A1 | |
| SCHEMBL9795057 | 0.82 | EPHX2 (0.33) | BCHEEPHX2 | |
| SCHEMBL9795256 | 0.81 | HSD11B1 (0.45) | HTTPOLBBCHEL3MBTL1LMNA | |
| SCHEMBL9795185 | 0.80 | KEAP1 (0.36) | BCHEEPHX2 | |
| SCHEMBL9795351 | 0.79 | FAAH (0.35) | DNM1POLBBCHEALDH1A1 | |
| SCHEMBL9499610 | 0.79 | FAAH (0.35) | DNM1POLBBCHEALDH1A1 | |
| SCHEMBL9497877 | 0.79 | FAAH (0.35) | DNM1POLBBCHEALDH1A1 | |
| SCHEMBL9498012 | 0.77 | PKM (0.40) | HTTPOLBBCHEL3MBTL1ALDH1A1 | |
| SCHEMBL9795150 | 0.77 | GSR (0.40) | DNM1HTTPOLBLGALS1BCHE | |
| SCHEMBL9795073 | 0.77 | TMEM97 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |