Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795276 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| Oxalic Acid SCHEMBL9795316 | 0.79 | FNTA (0.41) | ALDH1A1FAAHRECQLPTPN1 | |
| Oxalic Acid SCHEMBL9795337 | 0.78 | FNTA (0.43) | FAAHRECQLPTPN1 | |
| SCHEMBL9500008 | 0.73 | RECQL (0.42) | ALDH1A1FAAHRECQLPTPN1 | |
| SCHEMBL27665147 | 0.72 | PHF8 (0.46) | ALDH1A1LMNAFOLH1 | |
| SCHEMBL11222029 | 0.71 | FAAH (0.60) | FAAH | |
| SCHEMBL11653052 | 0.70 | CTSD (0.48) | ALDH1A1FAAHFOLH1 | |
| SCHEMBL21016147 | 0.69 | LMNA (0.41) | ALDH1A1FAAHLMNAPKMFOLH1 | |
| SCHEMBL3835414 | 0.69 | ALDH1A1 (0.62) | ALDH1A1FAAHHPGD | |
| SCHEMBL9226997 | 0.67 | FAAH (0.59) | ALDH1A1FAAHRECQLPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |