Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.54 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520528 | 0.85 | ALDH1A1 (0.55) | CDC7DBF4MAPTKDM4EMEN1 | |
| SCHEMBL29660779 | 0.84 | ALDH1A1 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL29660850 | 0.83 | ALDH1A1 (0.45) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL29660827 | 0.80 | ALDH1A1 (0.43) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL1194336 | 0.80 | TRPM8 (0.59) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL12332822 | 0.79 | ALDH1A1 (0.49) | TRPM8MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9795347 | 0.77 | TRPM8 (0.56) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL3921966 | 0.77 | ALDH1A1 (0.71) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL12591896 | 0.76 | ALDH1A1 (0.68) | CDC7DBF4TRPM8KDM4EMEN1 | |
| SCHEMBL28979284 | 0.75 | GAA (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-112778311-B | Nitrogen-containing fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-112778311-A | Nitrogen-containing fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-05-11 | — | — | CN | disclosed |
| US-5057142-A | Herbicidal thiazolecarboxamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| EP-0422470-A2 | Thiazolcarboxylic acid amide derivatives | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |