Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520528 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HPGDLMNAKDM4E | |
| SCHEMBL28979284 | 0.85 | GAA (0.52) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL9795341 | 0.84 | CDC7 (0.54) | ALDH1A1CYP1A2HPGDLMNAKDM4E | |
| SCHEMBL29660850 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL5731919 | 0.83 | MEN1 (0.45) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL2827636 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL22658446 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL29660827 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL9256013 | 0.80 | ALDH1A1 (0.70) | ALDH1A1CYP1A2HPGDLMNAGAA | |
| SCHEMBL12332822 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP1A2HPGDLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043450-A1 | NEW COMPOUND | JANSSEN PHARMACEUTICA NV (BE) | 2024-02-08 | — | — | US | disclosed |
| EP-4217347-A1 | NEW COMPOUNDS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022063896-A1 | NEW COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043450-A1 | NEW COMPOUND | NLRP3, NLRP1, PYCARD | ALDH1A1 1954/4885CYP1A2 1468/4885HPGD 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.