Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 2/20 | 0.31 |
| ▸ | ARG2 | P78540 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497704 | 0.94 | CFTR (0.31) | RIPK1 | |
| Oxalic Acid SCHEMBL9795145 | 0.81 | KDM4E (0.38) | RIPK1 | |
| SCHEMBL12335918 | 0.78 | RIPK1 (0.46) | RIPK1ARG1ARG2 | |
| Oxalic Acid SCHEMBL9795213 | 0.77 | CNR1 (0.32) | RIPK1 | |
| SCHEMBL6674518 | 0.75 | SMN1; SMN2 (0.35) | RIPK1 | |
| SCHEMBL7336172 | 0.74 | CA1 (0.38) | — | |
| SCHEMBL9499958 | 0.74 | KDM4E (0.38) | — | |
| Deanol SCHEMBL11871103 | 0.73 | MEN1 (0.37) | ARG1ARG2 | |
| Oxalic Acid SCHEMBL9795130 | 0.73 | L3MBTL1 (0.34) | — | |
| SCHEMBL12308385 | 0.73 | MMP8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |