Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795515 | 0.90 | ALOX5 (0.47) | ALOX5MGLL | |
| SCHEMBL9795591 | 0.84 | ALOX5 (0.59) | ALOX5MGLL | |
| SCHEMBL9795723 | 0.79 | MAPT (0.46) | ALOX5 | |
| SCHEMBL9644485 | 0.77 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL9795597 | 0.72 | ALOX5 (0.58) | ALOX5ADRB1MGLL | |
| SCHEMBL9795688 | 0.71 | MAPT (0.46) | ALOX5 | |
| SCHEMBL9795775 | 0.71 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL7829766 | 0.71 | HTR1A (0.48) | LPLLIPGDHFRPPARGPPARA | |
| SCHEMBL11823695 | 0.70 | ADRB2 (0.53) | LPLLIPGDHFRPPARGPPARA | |
| SCHEMBL9795613 | 0.69 | ALOX5 (0.59) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |