Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 11/20 | 0.48 |
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | HPD | P32754 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795700 | 0.90 | ALOX5 (0.53) | ALOX5MAOBGRM5DDB1CRBN | |
| SCHEMBL9795674 | 0.88 | ALOX5 (0.54) | ALOX5MAOBMAOAHPDGRM5 | |
| SCHEMBL9795565 | 0.80 | MAPT (0.43) | ALOX5MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9795723 | 0.80 | MAPT (0.46) | ALOX5MAOBMAOACRBNMEN1 | |
| SCHEMBL9795597 | 0.79 | ALOX5 (0.58) | ALOX5DDB1CRBNMEN1MAPT | |
| SCHEMBL9795640 | 0.78 | PDE3B (0.47) | ALOX5MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9795688 | 0.77 | MAPT (0.46) | ALOX5DDB1CRBNMEN1MAPT | |
| SCHEMBL9795754 | 0.75 | ALOX5 (0.54) | ALOX5MAPT | |
| SCHEMBL9795591 | 0.75 | ALOX5 (0.59) | ALOX5DDB1CRBN | |
| SCHEMBL9796084 | 0.75 | CTSG (0.45) | ALOX5MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |