Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.51 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795653 | 0.88 | ALOX5 (0.54) | ALOX5MAOBMAOAHPDDDB1 | |
| SCHEMBL9795700 | 0.87 | ALOX5 (0.53) | ALOX5MAOBDDB1CRBNTLR4 | |
| SCHEMBL9795564 | 0.78 | ALOX5 (0.56) | ALOX5KMT2AMEN1 | |
| SCHEMBL9795565 | 0.77 | MAPT (0.43) | ALOX5KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9795723 | 0.77 | MAPT (0.46) | ALOX5MAOBMAOACRBNTLR4 | |
| SCHEMBL9795597 | 0.76 | ALOX5 (0.58) | ALOX5DDB1CRBNKMT2AMEN1 | |
| SCHEMBL9795640 | 0.75 | PDE3B (0.47) | ALOX5KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL9795690 | 0.75 | ALOX5 (0.40) | ALOX5DDB1CRBNCYP2C9PKM | |
| SCHEMBL9796084 | 0.75 | CTSG (0.45) | ALOX5MAOBMAOA | |
| SCHEMBL9795570 | 0.75 | ALOX5 (0.43) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |